Genetic architecture of subcortical brain structures in 38,851 individuals.

L Satizabal, Claudia; H H Adams, Hieab; P Hibar, Derrek; C White, Charles; J Knol, Maria; L Stein, Jason; Scholz, Markus; Sargurupremraj, Muralidharan; Jahanshad, Neda; V Roshchupkin, Gennady; V Smith, Albert; C Bis, Joshua; Jian, Xueqiu; Luciano, Michelle; Hofer, Edith; Teumer, Alexander; J van der Lee, Sven; Yang, Jingyun; R Yanek, Lisa; V Lee, Tom; Li, Shuo; Hu, Yanhui; Yu Koh, Jia; D Eicher, John; Desrivières, Sylvane; Arias-Vasquez, Alejandro; Chauhan, Ganesh; Athanasiu, Lavinia; E Rentería, Miguel; Kim, Sungeun; Hoehn, David; J Armstrong, Nicola; Chen, Qiang; J Holmes, Avram; den Braber, Anouk; Kloszewska, Iwona; Andersson, Micael; Espeseth, Thomas; Grimm, Oliver; Abramovic, Lucija; Alhusaini, Saud; Milaneschi, Yuri; Papmeyer, Martina; Axelsson, Tomas; Ehrlich, Stefan; Roiz-Santiañez, Roberto; Kraemer, Bernd; K Håberg, Asta; J Jones, Hannah; Bruce Pike, G

doi:10.1038/s41588-019-0511-y

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Genetic architecture of subcortical brain structures in 38,851 individuals.

Published in Nature genetics • Nov 1, 2019

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Authors:

Claudia L Satizabal

,

Hieab H H Adams

,

Derrek P Hibar

Abstract

Subcortical brain structures are integral to motion, consciousness, emotions and learning. We identified common genetic variation related to the volumes of the nucleus accumbens, amygdala, brainstem, caudate nucleus, globus pallidus, putamen and thalamus, using genome-wide association analyses in al...

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