The Genetic Architecture of Parkinson Disease in Spain: Characterizing Population‐Specific Risk, Differential Haplotype Structures, and Providing Etiologic Insight

Bandrés‐Ciga, Sara; Ahmed, Sarah; S. Sabir, Marya; Blauwendraat, Cornelis; Adarmes‐Gómez, Astrid; Bernal‐Bernal, Inmaculada; Bonilla‐Toribio, Marta; Buiza‐Rueda, Dolores; Carrillo, Fátima; Carrión‐Claro, Mario; Gómez‐Garre, Pilar; Jesús, Silvia; A. Labrador‐Espinosa, Miguel; Macías, Daniel; Méndez‐del‐Barrio, Carlota; Teresa Periñán, María; Tejera‐Parrado, Cristina; Vargas‐González, Laura; Díez-Fairén, Mónica; Álvarez, Ignacio; Pablo Tartari, Juan; Buongiorno, Maríateresa; Aguilar, Miquel; Gorostidi, Ana; Bergareche, J; Mondragón, Elisabet; Vinagre‐Aragón, Ana; Croitoru, Ioana; Ruiz‐Martínez, Javier; Dols‐Icardo, Oriol; Kulisevsky, Jaime; Marín‐Lahoz, Juan; Pagonabarraga, Javier; Pascual‐Sedano, Berta; Ezquerra, Mario; Maria Novella Càmara, Anna; Compta, Yaroslau; Fernández, Manel; Fernández‐Santiago, Rubén; Muñoz, Esteban; Tolosa, Eduard; Valldeoriola, Francesc; González Aramburu, Isabel; Rodríguez, A; Sierra, María; Menéndez‐González, Manuel; Blázquez Estrada, Marta; García, Ciara; Suarez‐San Martin, Esther; Ruiz, Pedro; Carlos Martínez‐Castrillo, Juan; Vela, Lydia; Ruz, Clara; Javier Barrero, Francisco; Escamilla‐Sevilla, Francisco; Mínguez‐Castellanos, Adolfo; Cerdan, Debora; Tabernero, César; José Gómez Heredia, María; Pérez Errazquin, Francisco; Romero‐Acebal, Manolo; Feliz, Cici; Luis López-Sendón, José; Mata, Marina; Martínez‐Torres, Irene; Jeffrey Kim, Jonggeol; L. Dalgard, Clifton; Brooks, Janet; Sáez-Atiénzar, Sara; Raphael Gibbs, J.; Jorda, Rafael; A. Botía, Juan; Bonet‐Ponce, Luis; Morrison, Karen; E Clarke, Carl; Tan, Manuela; R. Morris, Huw; Edsall, Connor; Hernández, Dena; Simón‐Sánchez, Javier; A. Nalls, Mike; W. Scholz, Sonja; Jiménez‐Escrig, Adriano; Duarte, J.; Vives, Francisco; Durán, Raquel; Hoenicka, Janet; Álvarez, Victoria; Infante, Jon; José Martı́, Marı́a; Clarimón, Jordi; López de Munain, Adolfo; Pástor, Pau; Mir, Pablo; Singleton, Andrew

doi:10.1002/mds.27864

Public

The Genetic Architecture of Parkinson Disease in Spain: Characterizing Population‐Specific Risk, Differential Haplotype Structures, and Providing Etiologic Insight

Published in Movement Disorders • Oct 29, 2019

Authors:

Sara Bandrés‐Ciga

Sarah Ahmed

Marya S. Sabir

Abstract

BACKGROUND: The Iberian Peninsula stands out as having variable levels of population admixture and isolation, making Spain an interesting setting for studying the genetic architecture of neurodegenerative diseases. OBJECTIVES: To perform the largest PD genome-wide association study restricted to a s...

Subject

Haplotype

Parkinson's disease

Genetic architecture

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