Exacerbation of Chikungunya Virus Rheumatic Immunopathology by a High Fiber Diet and Butyrate

A. Prow, Natalie; Dominguez Crespo Hirata, Thiago; Tang, Bing; Larcher, Thibaut; Mukhopadhyay, Pamela; Lubiana Alves, Tiago; T. Le, Thuy; Gardner, Joy; Suan Poo, Yee; Nakayama, Eri; P. Lutzky, Viviana; I. Nakaya, Helder; Suhrbier, Andreas

doi:10.3389/fimmu.2019.02736

Public

Exacerbation of Chikungunya Virus Rheumatic Immunopathology by a High Fiber Diet and Butyrate

Published in Frontiers in Immunology • Nov 26, 2019

Authors:

Natalie A. Prow

Thiago Dominguez Crespo Hirata

Bing Tang

Abstract

Chikungunya virus (CHIKV) is a mosquito transmitted alphavirus associated with a robust systemic infection and an acute inflammatory rheumatic disease. A high fiber diet has been widely promoted for its ability to ameliorate inflammatory diseases. Fiber is fermented in the gut into short chain fatty...

Subject

Chikungunya

Exacerbation

Immunopathology

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