The histomolecular criteria established for adult anaplastic pilocytic astrocytoma are not applicable to the pediatric population

Gareton, Albane; Tauziède‐Espariat, Arnault; Dangouloff‐Ros, Volodia; Roux, Alexandre; Saffroy, Raphaël; Castel, David; Kergrohen, Thomas; Fina, Fréderic; Figarella‐Branger, Dominique; Pagès, Mélanie; Bourdeaut, Franck; Doz, François; Puget, Stéphanie; Dufour, Christelle; Lechapt, Emmanuèle; Chrétien, Fabrice; Grill, Jacques; Varlet, Pascale

doi:10.1007/s00401-019-02088-8

Public

The histomolecular criteria established for adult anaplastic pilocytic astrocytoma are not applicable to the pediatric population

Published in Acta Neuropathologica • Nov 1, 2019

Authors:

Albane Gareton

Arnault Tauziède‐Espariat

Volodia Dangouloff‐Ros

Abstract

Abstract Pilocytic astrocytoma (PA) is the most common pediatric glioma, arising from a single driver MAPK pathway alteration. Classified as a grade I tumor according to the 2016 WHO classification, prognosis is excellent with a 10-year survival rate > 95% after surgery. However, rare cases present ...

Subject

Anaplastic astrocytoma

Pilocytic astrocytoma

Methylation

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