Impact of breast cancer molecular subtypes on the incidence, kinetics and prognosis of central nervous system metastases in a large multicentre real-life cohort

Darlix, Amélie; Louvel, Guillaume; Fraisse, Julien; Jacot, William; Brain, Etienne; Debled, Marc; Ange Mouret-Reynier, Marie; Goncalves, Anthony; Dalenc, Florence; Delaloge, Suzette; Campone, Mario; Augereau, Paule; Marc Ferrero, Jean; Levy, Christelle; Fumet, Jean-David; Lecouillard, Isabelle; Cottu, Paul; Petit, Thierry; Uwer, Lionel; Jouannaud, Christelle; Leheurteur, Marianne; Dieras, Véronique; Robain, Mathieu; Chevrot, Michaël; Pasquier, David; Bachelot, Thomas

doi:10.1038/s41416-019-0619-y

Public

Impact of breast cancer molecular subtypes on the incidence, kinetics and prognosis of central nervous system metastases in a large multicentre real-life cohort

Shared by NobleBlocks on Nov 13, 2019 • 12:00 AM UTC

Authors:

Amélie Darlix

Guillaume Louvel

Julien Fraisse

Abstract

Abstract Background Metastatic breast cancer (MBC) behaviour differs depending on hormone receptors (HR) and human epidermal growth factor receptor (HER2) statuses. Methods The kinetics of central nervous system (CNS) metastases (CNS metastasis-free survival, CNSM-FS) and subsequent patient’s progno...

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