Natural Bis-Benzylisoquinoline Alkaloids-Tetrandrine, Fangchinoline, and Cepharanthine, Inhibit Human Coronavirus OC43 Infection of MRC-5 Human Lung Cells

Joon Kim, Dong; Min, Jung; Seong Jang, Min; Lee, Jun; Kee Shin, Young; Park, Chul; Suk Song, Jong; Rae Kim, Hyoung; Kim, Seungtaek; Jin, Young-Hee; Kwon, Sunoh

doi:10.3390/biom9110696

Public

Natural Bis-Benzylisoquinoline Alkaloids-Tetrandrine, Fangchinoline, and Cepharanthine, Inhibit Human Coronavirus OC43 Infection of MRC-5 Human Lung Cells

Published in Biomolecules • Nov 4, 2019

Authors:

Dong Joon Kim

Jung Min

Min Seong Jang

Abstract

are the major sources of the bis-benzylisoquinoline alkaloids tetrandrine (TET), fangchinoline (FAN), and cepharanthine (CEP). Although the pharmacological properties of these compounds include anticancer and anti-inflammatory activities, the antiviral effects of these compounds against human corona...

Subject

Tetrandrine

Benzylisoquinoline

Human lung

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