Combination Therapy with Oral Treprostinil for Pulmonary Arterial Hypertension. A Double-Blind Placebo-controlled Clinical Trial

James White, R.; Jerjes‐Sánchez, Carlos; Meyer, G.; Pulido, Tomás; Sepúlveda, Pablo; Yang Wang, Kuo; Grünig, Ekkehard; Hiremath, Shirish; Yu, Zaixin; Zhang, Gangcheng; Luen James Yip, Wei; Zhang, Shuyang; Khan, Akram; Q. Deng, C.; Grover, R.; F. Tapson, Victor

doi:10.1164/rccm.201908-1640oc

Public

Combination Therapy with Oral Treprostinil for Pulmonary Arterial Hypertension. A Double-Blind Placebo-controlled Clinical Trial

Published in American Journal of Respiratory and Critical Care Medicine • Nov 25, 2019

Authors:

R. James White

Carlos Jerjes‐Sánchez

G. Meyer

Abstract

Abstract Rationale Oral treprostinil improves exercise capacity in patients with pulmonary arterial hypertension (PAH), but the effect on clinical outcomes was unknown. Objectives To evaluate the effect of oral treprostinil compared with placebo on time to first adjudicated clinical worsening event ...

Subject

Treprostinil

Medicine

Placebo

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