Combined noninvasive metabolic and spindle imaging as potential tools for embryo and oocyte assessment

Sanchez, Tim; Venturas, Marta; Ali Aghvami, S.; Yang, Xingbo; Fraden, Seth; Sakkas, Denny; Needleman, Daniel

doi:10.1093/humrep/dez210

Public

Combined noninvasive metabolic and spindle imaging as potential tools for embryo and oocyte assessment

Published in Human Reproduction • Nov 5, 2019

Authors:

Tim Sanchez

Marta Venturas

S. Ali Aghvami

Abstract

STUDY QUESTION: Is the combined use of fluorescence lifetime imaging microscopy (FLIM)-based metabolic imaging and second harmonic generation (SHG) spindle imaging a feasible and safe approach for noninvasive embryo assessment? SUMMARY ANSWER: Metabolic imaging can sensitively detect meaningful meta...

Subject

Nicotinamide adenine dinucleotide

Blastocyst

Embryo

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