The MSC-Derived Exosomal lncRNA H19 Promotes Wound Healing in Diabetic Foot Ulcers by Upregulating PTEN via MicroRNA-152-3p

Li, Bo; Luan, Song; Chen, Jing; Zhou, Yue; Wang, Tingting; Li, Zhijuan; Fu, Yili; Zhai, Aixia; Bi, Changlong

doi:10.1016/j.omtn.2019.11.034

Public

The MSC-Derived Exosomal lncRNA H19 Promotes Wound Healing in Diabetic Foot Ulcers by Upregulating PTEN via MicroRNA-152-3p

Published in Molecular Therapy — Nucleic Acids • Dec 14, 2019

Authors:

Bo Li

Song Luan

Jing Chen

Abstract

Mesenchymal stem cells (MSCs) have been reported to hold promise to accelerate the wound-healing process in diabetic foot ulcer (DFU) due to the multilineage differentiation potential. Hence, this study intended to explore the wound healing role of MSC-derived exosomes containing long noncoding RNA ...

Subject

microRNA

Diabetic foot

PTEN

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