Quantitative IFN-γ Release Assay and Tuberculin Skin Test Results to Predict Incident Tuberculosis. A Prospective Cohort Study

K Gupta, Rishi; Lipman, Marc; Jackson, Charlotte; Sitch, Alice; Southern, Jo; Drobniewski, Francis; J Deeks, Jonathan; Tsou, Chuen-Yan; Griffiths, Chris; Davidson, Jennifer; Campbell, Colin; Stirrup, Oliver; Noursadeghi, Mahdad; Kunst, Heinke; Haldar, Pranabashis; Lalvani, Ajit; Abubakar, Ibrahim

doi:10.1164/rccm.201905-0969oc

Public

Quantitative IFN-γ Release Assay and Tuberculin Skin Test Results to Predict Incident Tuberculosis. A Prospective Cohort Study

Published in American Journal of Respiratory and Critical Care Medicine • Dec 11, 2019

Authors:

Rishi K Gupta

Marc Lipman

Charlotte Jackson

Abstract

Abstract Rationale Development of diagnostic tools with improved predictive value for tuberculosis (TB) is a global research priority. Objectives We evaluated whether implementing higher diagnostic thresholds than currently recommended for QuantiFERON Gold-in-Tube (QFT-GIT), T-SPOT.TB, and the tuber...

Subject

Medicine

Tuberculin

Tuberculosis

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