Randomised, multicentre prospective trial of transarterial chemoembolisation (TACE) plus sorafenib as compared with TACE alone in patients with hepatocellular carcinoma: TACTICS trial

Kudo, Masatoshi; Ueshima, Kazuomi; Ikeda, Masafumi; Torimura, Takuji; Tanabe, Nobukazu; Aikata, Hiroshi; Izumi, Namiki; Yamasaki, Takahiro; Nojiri, Shunsuke; Hino, Keisuke; Tsumura, Hidetaka; Kuzuya, Teiji; Isoda, Norio; Yasui, Kohichiroh; Aino, Hajime; Ido, Akio; Kawabe, Naoto; Nakao, Kazuhiko; Wada, Yoshiyuki; Yokosuka, Osamu; Yoshimura, Kenichi; Okusaka, Takuji; Furuse, Junji; Kokudo, Norihiro; Okita, Kiwamu; James Johnson, Philip; Arai, Yasuaki

doi:10.1136/gutjnl-2019-318934

Public

Randomised, multicentre prospective trial of transarterial chemoembolisation (TACE) plus sorafenib as compared with TACE alone in patients with hepatocellular carcinoma: TACTICS trial

Shared by NobleBlocks on Dec 4, 2019 • 12:00 AM UTC

Authors:

Masatoshi Kudo

Kazuomi Ueshima

Masafumi Ikeda

Abstract

Objective This trial compared the efficacy and safety of transarterial chemoembolisation (TACE) plus sorafenib with TACE alone using a newly established TACE-specific endpoint and pre-treatment of sorafenib before initial TACE. Design Patients with unresectable hepatocellular carcinoma (HCC) were ra...

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