Effect of <i>Clostridium butyricum</i> against Microglia‐Mediated Neuroinflammation in Alzheimer's Disease via Regulating Gut Microbiota and Metabolites Butyrate

Sun, Jing; Xu, Jing‐Xuan; Yang, Bo; Chen, Keyang; Kong, Yu; Fang, Na; Gong, Tianyu; Wang, Fangyan; Ling, Zongxin; Liu, Jiaming

doi:10.1002/mnfr.201900636

Public

Effect of Clostridium butyricum against Microglia‐Mediated Neuroinflammation in Alzheimer's Disease via Regulating Gut Microbiota and Metabolites Butyrate

Published in Molecular Nutrition & Food Research • Dec 13, 2019

Authors:

Jing Sun

Jing‐Xuan Xu

Bo Yang

Abstract

SCOPE: Recent evidences demonstrate that abnormal gut microbiota (GM) might be involved in the pathogenesis of Alzheimer's disease (AD). However, the role of probiotics in preventing AD by regulating GM-gut-brain axis remains unclear. Here, the anti-neuroinflammatory effect and its mechanism of prob...

Subject

Neuroinflammation

Clostridium butyricum

Microglia

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