Protective Effects of Chlorogenic Acid on Cerebral Ischemia/Reperfusion Injury Rats by Regulating Oxidative Stress-Related Nrf2 Pathway.

Liu, Dequan; Wang, Huilin; Zhang, Yangang; Zhang, Zhan

doi:10.2147/dddt.s228751

Public

Protective Effects of Chlorogenic Acid on Cerebral Ischemia/Reperfusion Injury Rats by Regulating Oxidative Stress-Related Nrf2 Pathway.

Shared by NobleBlocks on Jan 1, 2020 • 12:00 AM UTC

Authors:

Dequan Liu

Huilin Wang

Yangang Zhang

Abstract

INTRODUCTION: Cerebral ischemia-reperfusion (CI/R) injury is caused by blood flow recovery after ischemic stroke. Chlorogenic acid (CGA, 5-O-caffeoylquinic acid) is a major polyphenol component of Coffea canephora, Coffea arabica L. and Mate (Ilex paraguariensis A. StHil.). Previous studies have sho...

Subject

NF-E2-related factor 2 pathway

cerebral ischemia/reperfusion injury

chlorogenic acid

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