&lt;p&gt;Protective Effects of Chlorogenic Acid on Cerebral Ischemia/Reperfusion Injury Rats by Regulating Oxidative Stress-Related Nrf2 Pathway&lt;/p&gt;

Liu, Dequan; Wang, Huilin; Zhang, Yangang; Zhang, Zhan

doi:10.2147/dddt.s228751

Public

<p>Protective Effects of Chlorogenic Acid on Cerebral Ischemia/Reperfusion Injury Rats by Regulating Oxidative Stress-Related Nrf2 Pathway</p>

Published in Drug Design Development and Therapy • Jan 1, 2020

Authors:

Dequan Liu

Huilin Wang

Yangang Zhang

Abstract

Introduction: Cerebral ischemia-reperfusion (CI/R) injury is caused by blood flow recovery after ischemic stroke. Chlorogenic acid (CGA, 5-O-caffeoylquinic acid) is a major polyphenol component of Coffea canephora, Coffea arabica L. and Mate ( Ilex paraguariensis A. StHil .). Previous studies have s...

Subject

Oxidative stress

Neuroprotection

TUNEL assay

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