An injectable thermosensitive hydrogel loaded with an ancient natural drug colchicine for myocardial repair after infarction

Chen, Yu; Shi, Jiayue; Zhang, Yaping; Miao, Jiajun; Zhao, Zhe; Jin, Xian; Liu, Liang; Yu, Lin; Shen, Chengxing; Ding, Jiandong

doi:10.1039/c9tb02523e

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An injectable thermosensitive hydrogel loaded with an ancient natural drug colchicine for myocardial repair after infarction

Published in Journal of Materials Chemistry B • Dec 31, 2019

Authors:

Yu Chen

Jiayue Shi

Yaping Zhang

Abstract

Localized administration of anti-inflammatory agents benefits patients after myocardial infarction (MI) by repressing/modulating inflammatory response of the MI region and thus accelerating repair of the impaired tissues. Colchicine (Col), an ancient natural drug, has excellent anti-inflammatory eff...

Subject

Colchicine

Myocardial infarction

Drug

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