The antibody response induced FMDV vaccines in sheep correlates with early transcriptomic responses in blood

Jouneau, Luc; Lefebvre, David; Costa, Fleur; Romey, Aurore; Blaise‐Boisseau, Sandra; Relmy, Anthony; Jaszczyszyn, Yan; Dard-Dascot, Cloelia; Dejean, Sébastien; Versillé, Nicolas; Guitton, Édouard; Hudelet, Pascal; Curet, Marianne; De Clercq, Kris; Bakkali‐Kassimi, Labib; Zientara, Stéphan; Klonjkowski, Bernard; Schwartz-Cornil, Isabelle

doi:10.1038/s41541-019-0151-3

Public

The antibody response induced FMDV vaccines in sheep correlates with early transcriptomic responses in blood

Published in npj Vaccines • Jan 3, 2020

Authors:

Luc Jouneau

David Lefebvre

Fleur Costa

Abstract

Foot and mouth disease (FMD) is a highly contagious viral disease with high economic impact, representing a major threat for cloven-hooved mammals worldwide. Vaccines based on adjuvanted inactivated virus (iFMDV) induce effective protective immunity implicating antibody (Ab) responses. To reduce the...

Subject

Immunogenicity

Adjuvant

Virology

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