Translocator protein–mediated fast-onset antidepressant-like and memory-enhancing effects in chronically stressed mice

Shang, Chao; Yao, Rumeng; Guo, Ying; Ding, Zhen-Chun; Sun, Lijun; Ran, Yuhua; Xue, Rui; Wang, Huaishan; Zhang, Jianmin; Zhang, You‐Zhi; Zhang, Liming; Li, Yunfeng

doi:10.1177/0269881119896304

Public

Translocator protein–mediated fast-onset antidepressant-like and memory-enhancing effects in chronically stressed mice

Published in Journal of Psychopharmacology • Jan 8, 2020

Authors:

Chao Shang

Rumeng Yao

Ying Guo

Abstract

BACKGROUND: Fast-acting and cognitive-enhancing antidepressants are desperately needed. Activation of translocator protein (18 kDa, TSPO) is a novel strategy for developing potential antidepressants, but there are no data available on the onset time of TSPO ligands. This study aimed to investigate t...

Subject

Translocator protein

Antidepressant

Pharmacology

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!