Engineered exosomes for targeted co-delivery of miR-21 inhibitor and chemotherapeutics to reverse drug resistance in colon cancer.
Published in Journal of nanobiotechnology • Jan 9, 2020
Authors:,,
Gaofeng Liang
Yanliang Zhu
Doulathunnisa Jaffar Ali
Abstract
BACKGROUND: 5-Fluorouracil (5-FU) has been commonly prescribed for patients with colorectal cancer (CRC), but resistance to 5-FU is one of the main reasons for failure in CRC. Recently, microRNAs (miRNAs) have been established as a means of reversing the dilemma by regulating signaling pathways invo...
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