A Randomized Trial of Erythropoietin for Neuroprotection in Preterm Infants

E. Juul, Sandra; A. Comstock, Bryan; Wadhawan, Rajan; E. Mayock, Dennis; E. Courtney, Sherry; Robinson, Tonya; A. Ahmad, Kaashif; Bendel‐Stenzel, Ellen; Baserga, Mariana; F. LaGamma, Edmund; Corbin Downey, L.; Rao, Raghavendra; Fahim, Nancy; Lampland, Andrea; D. Frantz, Ivan; Y. Khan, Janine; Weiss, Michael; Gilmore, Maureen; K. Ohls, Robin; Srinivasan, Nishant; Perez, Jorge; McKay, Victor; T. Vu, Phuong; Lowe, Jean; Kuban, Karl; Michael O’Shea, T.; L. Hartman, Adam; J. Heagerty, Patrick

doi:10.1056/nejmoa1907423

Public

A Randomized Trial of Erythropoietin for Neuroprotection in Preterm Infants

Published in New England Journal of Medicine • Jan 15, 2020

Authors:

Sandra E. Juul

Bryan A. Comstock

Rajan Wadhawan

Abstract

BACKGROUND: High-dose erythropoietin has been shown to have a neuroprotective effect in preclinical models of neonatal brain injury, and phase 2 trials have suggested possible efficacy; however, the benefits and safety of this therapy in extremely preterm infants have not been established. METHODS: ...

Subject

Neuroprotection

Erythropoietin

Randomized controlled trial

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