A comparison of methods for the isolation and separation of extracellular vesicles from protein and lipid particles in human serum

Brennan, Kieran; Martin, Katrin; P. Fitzgerald, S.; O’Sullivan, Jeff; Wu, Yunjie; Blanco, Alfonso; Richardson, Ciarán; M. Mc Gee, Margaret

doi:10.1038/s41598-020-57497-7

Public

A comparison of methods for the isolation and separation of extracellular vesicles from protein and lipid particles in human serum

Published in Scientific Reports • Jan 23, 2020

Authors:

Kieran Brennan

Katrin Martin

S. P. Fitzgerald

Abstract

Extracellular vesicles (EVs) are nano-sized vesicles containing nucleic acid and protein cargo that are released from a multitude of cell types and have gained significant interest as potential diagnostic biomarkers. Human serum is a rich source of readily accessible EVs; however, the separation of ...

Subject

Extracellular vesicles

Isolation (microbiology)

Extracellular

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