Transmission of Rat Hepatitis E Virus Infection to Humans in Hong Kong: A Clinical and Epidemiological Analysis

Sridhar, Siddharth; Chik‐Yan Yip, Cyril; Wu, Shusheng; Foo‐Siong Chew, Nicholas; Leung, Kit‐Hang; Fuk‐Woo Chan, Jasper; Zhao, Suhui; Chan, Wan‐Mui; Wing‐Shan Poon, Rosana; Tsoi, Hoi‐Wah; Cai, Jian‐Piao; Shuk‐Ying Chan, Helen; Wai‐Shing Leung, Anthony; Wing‐Sze Tse, Cindy; Sze‐Tsing Zee, Jonpaul; Tak‐Yin Tsang, Owen; Chi‐Chung Cheng, Vincent; K. P. Lau, Susanna; C. Y. Woo, Patrick; Ngai‐Chong Tsang, Dominic; Yuen, Kwok‐Yung

doi:10.1002/hep.31138

Public

Transmission of Rat Hepatitis E Virus Infection to Humans in Hong Kong: A Clinical and Epidemiological Analysis

Published in Hepatology • Jan 21, 2020

Authors:

Siddharth Sridhar

Cyril Chik‐Yan Yip

Shusheng Wu

Abstract

BACKGROUND AND AIMS: Hepatitis E virus (HEV) variants causing human infection predominantly belong to HEV species A (HEV-A). HEV species C genotype 1 (HEV-C1) circulates in rats and is highly divergent from HEV-A. It was previously considered unable to infect humans, but the first case of human HEV-...

Subject

Hepatitis E virus

Subclinical infection

Virology

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