Cerebrospinal fluid lipocalin 2 as a novel biomarker for the differential diagnosis of vascular dementia

Llorens, Franc; Hermann, Péter; Villar‐Piqué, Anna; Díaz‐Lucena, Daniela; Nägga, Katarina; Hansson, Oskar; Santana, Isabel; Schmitz, Matthias; Schmidt, Christian; Varges, Daniela; Goebel, Stefan; Dumurgier, Julien; Zetterberg, Henrik; Blennow, Kaj; Paquet, Claire; Baldeiras, Inês; Ferrer, Isidró; Zerr, Inga

doi:10.1038/s41467-020-14373-2

Public

Cerebrospinal fluid lipocalin 2 as a novel biomarker for the differential diagnosis of vascular dementia

Published in Nature Communications • Jan 30, 2020

Authors:

Franc Llorens

Péter Hermann

Anna Villar‐Piqué

Abstract

The clinical diagnosis of vascular dementia (VaD) is based on imaging criteria, and specific biochemical markers are not available. Here, we investigated the potential of cerebrospinal fluid (CSF) lipocalin 2 (LCN2), a secreted glycoprotein that has been suggested as mediating neuronal damage in vas...

Subject

Cerebrospinal fluid

Biomarker

Dementia

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