Industrialization is associated with elevated rates of horizontal gene transfer in the human microbiome

Groussin, Mathieu; Poyet, Mathilde; Sistiaga, Ainara; M. Kearney, Sean; Moniz, Katya; Noel, Mary; Hooker, Jeff; M. Gibbons, Sean; Ségurel, Laure; Froment, Alain; Saïd-Mohamed, Rihlat; Fezeu, Alain; A. Juimo, Vanessa; Girard, Catherine; Thanh Tu Nguyen, Le; Jesse Shapiro, B.; Lehtimäki, Jenni; Ruokolainen, Lasse; Kettunen, Pinja; Vatanen, Tommi; Sigwazi, Shani; Mabulla, Audax; Domínguez‐Rodrigo, Manuel; E. Summons, Roger; J. Xavier, Ramnik; J. Alm, Eric

doi:10.1101/2020.01.28.922104

Public

Industrialization is associated with elevated rates of horizontal gene transfer in the human microbiome

Published in bioRxiv (Cold Spring Harbor Laboratory) • Jan 29, 2020

Authors:

Mathieu Groussin

Mathilde Poyet

Ainara Sistiaga

Abstract

Abstract Horizontal Gene Transfer, the process by which bacteria acquire new genes and functions from non-parental sources, is common in the human microbiome 1,2 . If the timescale of HGT is rapid compared to the timescale of human colonization, then it could have the effect of ‘personalizing’ bacte...

Subject

Horizontal gene transfer

Microbiome

Biology

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