Plasma Circulating Tumor HPV DNA for the Surveillance of Cancer Recurrence in HPV-Associated Oropharyngeal Cancer

S. Chera, Bhishamjit; Kumar, Sunil; J. Shen, Colette; J. Amdur, Robert; Dagan, Roi; Green, Rebecca; C. Goldman, Emily; Weiss, Jared; E. Grilley‐Olson, Juneko; Patel, Shetal; M. Zanation, Adam; Hackman, Trevor; Blumberg, Jeff; Patel, Samip; D. Thorp, Brian; C. Weissler, Mark; G. Yarbrough, Wendell; Sheets, Nathan; M. Mendenhall, William; Tan, Xianming; P. Gupta, Gaorav

doi:10.1200/jco.19.02444

Public

Plasma Circulating Tumor HPV DNA for the Surveillance of Cancer Recurrence in HPV-Associated Oropharyngeal Cancer

Published in Journal of Clinical Oncology • Feb 4, 2020

Authors:

Bhishamjit S. Chera

Sunil Kumar

Colette J. Shen

Abstract

PURPOSE: Plasma circulating tumor human papillomavirus DNA (ctHPVDNA) is a sensitive and specific biomarker of human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (OPSCC). We investigated whether longitudinal monitoring of ctHPVDNA during post-treatment surveillance could acc...

Subject

Medicine

Internal medicine

Biomarker

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