Plasma Exchange and Glucocorticoids in Severe ANCA-Associated Vasculitis

Walsh, Michael; A. Merkel, Peter; Au Peh, Chen; Szpirt, Wladimir; Puéchal, Xavier; Fujimoto, Shouichi; M. Hawley, Carmel; Khalidi, Nader; Floßmann, Oliver; Wald, Ron; Girard, Louis; Levin, Adeera; Gregorini, Gina; Harper, Lorraine; F. Clark, William; Pagnoux, Christian; Specks, Ulrich; Smyth, Lucy; Tesař, Vladimı́r; Ito‐Ihara, Toshiko; de Zoysa, Janak; Szczeklik, Wojciech; Felipe Flores-Suárez, Luis; Carette, Simon; Guillevin, Loı̈c; D. Pusey, Charles; Casian, Alina; Brezina, Biljana; Mazzetti, Andrea; A. McAlear, Carol; Broadhurst, Elizabeth; Reidlinger, Donna; Mehta, Samir; Ives, Natalie; Jayne, David

doi:10.1056/nejmoa1803537

Public

Plasma Exchange and Glucocorticoids in Severe ANCA-Associated Vasculitis

Published in New England Journal of Medicine • Feb 12, 2020

Authors:

Michael Walsh

Peter A. Merkel

Chen Au Peh

Abstract

BACKGROUND: More effective and safer treatments are needed for antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis. METHODS: of body-surface area or diffuse pulmonary hemorrhage). Patients were randomly assigned to undergo plasma exchange (seven plasma exchanges within 14 days after ran...

Subject

Vasculitis

ANCA-Associated Vasculitis

Anti-neutrophil cytoplasmic antibody

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