Genomic surveillance for hypervirulence and multi-drug resistance in invasive Klebsiella pneumoniae from South and Southeast Asia

L. Wyres, Kelly; Nguyen Thi Nguyen, To; M. C. Lam, Margaret; M. Judd, Louise; Văn Vĩnh Châu, Nguyễn; A. B. Dance, David; Ip, Margaret; Karkey, Abhilasha; Ling, Clare; Miliya, Thyl; N. Newton, Paul; Phu Huong Lan, Nguyen; Sengduangphachanh, Amphone; Turner, Paul; Veeraraghavan, Balaji; Voong Vinh, Phat; Vongsouvath, Manivanh; R. Thomson, Nicholas; Baker, Stephen; E. Holt, Kathryn

doi:10.1186/s13073-019-0706-y

Public

Genomic surveillance for hypervirulence and multi-drug resistance in invasive Klebsiella pneumoniae from South and Southeast Asia

Published in Genome Medicine • Jan 16, 2020

Authors:

Kelly L. Wyres

To Nguyen Thi Nguyen

Margaret M. C. Lam

Abstract

BACKGROUND: Klebsiella pneumoniae is a leading cause of bloodstream infection (BSI). Strains producing extended-spectrum beta-lactamases (ESBLs) or carbapenemases are considered global priority pathogens for which new treatment and prevention strategies are urgently required, due to severely limited...

Subject

Klebsiella pneumoniae

Drug resistance

Human genetics

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