ROS in cancer therapy: the bright side of the moon

Perillo, Bruno; Di Donato, Marzia; Pezone, Antonio; Di Zazzo, Erika; Giovannelli, Pia; Galasso, Giovanni; Castoria, Gabriella; Migliaccio, Antimo

doi:10.1038/s12276-020-0384-2

Public

ROS in cancer therapy: the bright side of the moon

Published in Experimental & Molecular Medicine • Feb 1, 2020

Authors:

Bruno Perillo

Marzia Di Donato

Antonio Pezone

Abstract

Reactive oxygen species (ROS) constitute a group of highly reactive molecules that have evolved as regulators of important signaling pathways. It is now well accepted that moderate levels of ROS are required for several cellular functions, including gene expression. The production of ROS is elevated...

Subject

Reactive oxygen species

Signal transduction

DNA damage

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