Effect of Vancomycin or Daptomycin With vs Without an Antistaphylococcal β-Lactam on Mortality, Bacteremia, Relapse, or Treatment Failure in Patients With MRSA Bacteremia

Y. C. Tong, Steven; Chien Lye, David; Yahav, Dafna; Sud, Archana; O. Robinson, James; Nelson, Jane; Archuleta, Sophia; A. Roberts, Matthew; Cass, Alan; L. Paterson, David; Foo, Hong; Paul, Mical; Guy, Stephen; R Tramontana, Adrian; Walls, Genevieve; McBride, Stephen; Bak, Narin; Ghosh, Niladri; A. Rogers, Benjamin; P. Ralph, Anna; Davies, Jane; E. Ferguson, Patricia; Dotel, Ravindra; McKew, Genevieve; Gray, Timothy; E. Holmes, Natasha; Smith, Simon; S. Warner, Morgyn; Kalimuddin, Shirin; Edward Young, Barnaby; Runnegar, Naomi; Andresen, David; Anagnostou, Nicholas; Johnson, Sandra; D. Chatfield, Mark; Cheng, Allen; G. Fowler, Vance; P. Howden, Benjamin; Meagher, Niamh; J. Price, David; J. van Hal, Sebastiaan; O’Sullivan, Matthew; S. Davis, Joshua

doi:10.1001/jama.2020.0103

Public

Effect of Vancomycin or Daptomycin With vs Without an Antistaphylococcal β-Lactam on Mortality, Bacteremia, Relapse, or Treatment Failure in Patients With MRSA Bacteremia

Published in JAMA • Feb 11, 2020

Authors:

Steven Y. C. Tong

David Chien Lye

Dafna Yahav

Abstract

Importance: Methicillin-resistant Staphylococcus aureus (MRSA) bacteremia is associated with mortality of more than 20%. Combining standard therapy with a β-lactam antibiotic has been associated with reduced mortality, although adequately powered randomized clinical trials of this intervention have ...

Subject

Medicine

Bacteremia

Daptomycin

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!