A microcarrier-based spheroid 3D invasion assay to monitor dynamic cell movement in extracellular matrix

Liu, Hui; Lu, Tao; Kremers, Gert‐Jan; L.B. Seynhaeve, Ann; L.M. ten Hagen, Timo

doi:10.1186/s12575-019-0114-0

Public

A microcarrier-based spheroid 3D invasion assay to monitor dynamic cell movement in extracellular matrix

Published in Biological Procedures Online • Feb 1, 2020

Authors:

Hui Liu

Tao Lu

Gert‐Jan Kremers

Abstract

BACKGROUND: Cell invasion through extracellular matrix (ECM) is a critical step in tumor metastasis. To study cell invasion in vitro, the internal microenvironment can be simulated via the application of 3D models. RESULTS: This study presents a method for 3D invasion examination using microcarrier-...

Subject

Microcarrier

Spheroid

Extracellular matrix

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!