LncRNA LINC00662 promotes colon cancer tumor growth and metastasis by competitively binding with miR-340-5p to regulate CLDN8/IL22 co-expression and activating ERK signaling pathway.

B, Cheng; A, Rong; Q, Zhou; W, Li

doi:10.1186/s13046-019-1510-7

Public

LncRNA LINC00662 promotes colon cancer tumor growth and metastasis by competitively binding with miR-340-5p to regulate CLDN8/IL22 co-expression and activating ERK signaling pathway.

Shared by NobleBlocks on Jan 3, 2020 • 12:00 AM UTC

Authors:

Cheng B

Rong A

Zhou Q

Abstract

Background LncRNA LINC00662 is closely related to the occurrence and development of cancer. This study aims to explore the effect of LINC00662 on colon cancer tumor growth and metastasis and its molecular mechanism.Methods CCK8, colony formation, transwell, scratch wound, TUNEL, flow cytometry, RT-P...

Subject

Growth

Metastasis

Colon cancer

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