Improved Molecular Diagnosis of COVID-19 by the Novel, Highly Sensitive and Specific COVID-19-RdRp/Hel Real-Time Reverse Transcription-PCR Assay Validated <i>In Vitro</i> and with Clinical Specimens

Fuk‐Woo Chan, Jasper; Chik‐Yan Yip, Cyril; Kai‐Wang To, Kelvin; Hing‐Cheung Tang, Tommy; C. Y. Wong, Sally; Leung, Kit‐Hang; Yim-Fong Fung, Agnes; Chin‐Ki Ng, Anthony; Zou, Zijiao; Tsoi, Hoi‐Wah; Kwan-Yue Choi, Garnet; Raymond Tam, Anthony; Chi‐Chung Cheng, Vincent; Chan, Kwok‐Hung; Tak‐Yin Tsang, Owen; Yuen, Kwok‐Yung

doi:10.1128/jcm.00310-20

Public

Improved Molecular Diagnosis of COVID-19 by the Novel, Highly Sensitive and Specific COVID-19-RdRp/Hel Real-Time Reverse Transcription-PCR Assay Validated In Vitro and with Clinical Specimens

Published in Journal of Clinical Microbiology • Mar 5, 2020

Authors:

Jasper Fuk‐Woo Chan

Cyril Chik‐Yan Yip

Kelvin Kai‐Wang To

Abstract

On 31 December 2019, the World Health Organization was informed of a cluster of cases of pneumonia of unknown etiology in Wuhan, China. Subsequent investigations identified a novel coronavirus, now named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), from the affected patients. Highly...

Subject

Virology

Biology

Coronavirus

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