Role of oxidative stress in the pathogenesis of nonalcoholic fatty liver disease

Chen, Ze; Tian, Ruifeng; She, Zhi‐Gang; Cai, Jingjing; Li, Hongliang

doi:10.1016/j.freeradbiomed.2020.02.025

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Role of oxidative stress in the pathogenesis of nonalcoholic fatty liver disease

Published in Free Radical Biology and Medicine • Mar 8, 2020

Authors:

Ze Chen

Ruifeng Tian

Zhi‐Gang She

Abstract

Nonalcoholic fatty liver disease (NAFLD) has emerged as the most common chronic liver disease worldwide and is strongly associated with the presence of oxidative stress. Disturbances in lipid metabolism lead to hepatic lipid accumulation, which affects different reactive oxygen species (ROS) generat...

Subject

Nonalcoholic fatty liver disease

Oxidative stress

Reactive oxygen species

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