Treatment of Highly Drug-Resistant Pulmonary Tuberculosis

Conradie, Francesca; H. Diacon, Andreas; Ngubane, Nosipho; Howell, Pauline; E. Everitt, Daniel; M. Crook, Angela; M. Mendel, Carl; Egizi, Erica; Moreira, Joanna; Timm, Juliano; D. McHugh, Timothy; H. Wills, Genevieve; Bates, Matthew; Hunt, Robert; van Niekerk, Christo; Li, Mengchun; Olugbosi, Morounfolu; Spigelman, Melvin

doi:10.1056/nejmoa1901814

Public

Treatment of Highly Drug-Resistant Pulmonary Tuberculosis

Published in New England Journal of Medicine • Mar 4, 2020

Authors:

Francesca Conradie

Andreas H. Diacon

Nosipho Ngubane

Abstract

BACKGROUND: Patients with highly drug-resistant forms of tuberculosis have limited treatment options and historically have had poor outcomes. METHODS: In an open-label, single-group study in which follow-up is ongoing at three South African sites, we investigated treatment with three oral drugs - be...

Subject

Tuberculosis

Drug

Medicine

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