Single-cell analysis of human ovarian cortex identifies distinct cell populations but no oogonial stem cells

Wagner, Magdalena; Yoshihara, Masahito; Douagi, Iyadh; Damdimopoulos, Anastasios; Panula, Sarita; Petropoulos, Sophie; Lu, Haojiang; Pettersson, Karin; Palm, Kerstin; Katayama, Shintaro; Hovatta, Outi; Kere, Juha; Lanner, Fredrik; Damdimopoulou, Pauliina

doi:10.1038/s41467-020-14936-3

Public

Single-cell analysis of human ovarian cortex identifies distinct cell populations but no oogonial stem cells

Published in Nature Communications • Mar 2, 2020

Authors:

Magdalena Wagner

Masahito Yoshihara

Iyadh Douagi

Abstract

The human ovary orchestrates sex hormone production and undergoes monthly structural changes to release mature oocytes. The outer lining of the ovary (cortex) has a key role in defining fertility in women as it harbors the ovarian reserve. It has been postulated that putative oogonial stem cells exi...

Subject

Ovarian Cortex

Biology

Ovary

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