<i>De novo</i> assembly of the cattle reference genome with single-molecule sequencing

D Rosen, Benjamin; M Bickhart, Derek; D Schnabel, Robert; Koren, Sergey; G Elsik, Christine; Tseng, Elizabeth; N Rowan, Troy; Y Low, Wai; Zimin, Aleksey; Couldrey, Christine; Hall, Richard; Li, Wenli; Rhie, Arang; Ghurye, Jay; D McKay, Stephanie; Thibaud-Nissen, Françoise; Hoffman, Jinna; M Murdoch, Brenda; M Snelling, Warren; G McDaneld, Tara; A Hammond, John; C Schwartz, John; Nandolo, Wilson; E Hagen, Darren; Dreischer, Christian; J Schultheiss, Sebastian; G Schroeder, Steven; M Phillippy, Adam; B Cole, John; P Van Tassell, Curtis; Liu, George; P L Smith, Timothy; F Medrano, Juan

doi:10.1093/gigascience/giaa021

Public

De novo assembly of the cattle reference genome with single-molecule sequencing

Shared by NobleBlocks on Mar 1, 2020 • 12:00 AM UTC

Authors:

Benjamin D Rosen

Derek M Bickhart

Robert D Schnabel

Abstract

Abstract Background Major advances in selection progress for cattle have been made following the introduction of genomic tools over the past 10–12 years. These tools depend upon the Bos taurus reference genome (UMD3.1.1), which was created using now-outdated technologies and is hindered by a variety...

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