Terminally Differentiated Effector Memory CD8+ T Cells Identify Kidney Transplant Recipients at High Risk of Graft Failure

Jacquemont, Lola; Tilly, Gaëlle; Yap, Michelle; Doan-Ngoc, Tra-My; Danger, Richard; Guérif, Pierrick; Delbos, Florent; Martinet, Bernard; Giral, Magali; Foucher, Yohann; Brouard, Sophie; Degauque, Nicolas

doi:10.1681/asn.2019080847

Public

Terminally Differentiated Effector Memory CD8+ T Cells Identify Kidney Transplant Recipients at High Risk of Graft Failure

Published in Journal of the American Society of Nephrology • Mar 12, 2020

Authors:

Lola Jacquemont

Gaëlle Tilly

Michelle Yap

Abstract

Significance Statement Identifying biomarkers for predicting kidney transplant failure requires better understanding of the immune response to chronic allogeneic stimulation. The authors demonstrated that 1 year after kidney transplantation, the composition of CD8 + memory T cell subsets in blood—sp...

Subject

Immunology

CD8

Cytotoxic T cell

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