Docetaxel-loaded solid lipid nanoparticles prevent tumor growth and lung metastasis of 4T1 murine mammary carcinoma cells

Cristina Oliveira da Rocha, Márcia; Bento da Silva, Patrícia; Arantes Radicchi, Marina; Yasmin Garcia Andrade, Bárbara; Vaz de Oliveira, Jaqueline; Venus, Tom; Merker, Carolin; Estrela‐Lopis, Irina; Paulo Figueiró Longo, João; Nair Báo, Sônia

doi:10.1186/s12951-020-00604-7

Public

Docetaxel-loaded solid lipid nanoparticles prevent tumor growth and lung metastasis of 4T1 murine mammary carcinoma cells

Published in Journal of Nanobiotechnology • Mar 12, 2020

Authors:

Márcia Cristina Oliveira da Rocha

Patrícia Bento da Silva

Marina Arantes Radicchi

Abstract

Abstract Background Metastasis causes the most breast cancer-related deaths in women. Here, we investigated the antitumor effect of solid lipid nanoparticles (SLN-DTX) when used in the treatment of metastatic breast tumors using 4T1-bearing BALB/c mice. Results Solid lipid nanoparticles (SLNs) were ...

Subject

Solid lipid nanoparticle

Docetaxel

Chemistry

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