Aberrant gut microbiota alters host metabolome and impacts renal failure in humans and rodents

Wang, Xifan; Yang, Songtao; Li, Shenghui; Zhao, Liang; Hao, Yanling; Qin, Junjie; Zhang, Lian; Zhang, Chengying; Bian, Weijing; Zuo, Li; Kun Gao, Xiu; Zhu, Baoli; Gen Lei, Xin; Gu, Zhenglong; Cui, Wei; Xu, Xiping; Li, Zhiming; Zhu, Benzhong; Li, Yuan; Chen, Shangwu; Guo, Huiyuan; Zhang, Hao; Sun, Jing; Zhang, Ming; Yan, Hui; Zhang, Xiaolin; Liu, Xiaoxue; Sun, Bowen; Wang, Longjiao; Qiu, Qinglu; Zhang, Yuchan; Li, Xingqi; Liu, Weiqian; Xue, Rui; Wu, Hong; Shao, Donghua; Li, Junling; Zhou, Yuanjie; Li, Shaochuan; Yang, Rentao; Pedersen, Oluf; Yu, Zhengquan; Dusko Ehrlich, S.; Ren, Fazheng

doi:10.1136/gutjnl-2019-319766

Public

Aberrant gut microbiota alters host metabolome and impacts renal failure in humans and rodents

Published in Gut • Apr 2, 2020

Authors:

Xifan Wang

Songtao Yang

Shenghui Li

Abstract

Objective Patients with renal failure suffer from symptoms caused by uraemic toxins, possibly of gut microbial origin, as deduced from studies in animals. The aim of the study is to characterise relationships between the intestinal microbiome composition, uraemic toxins and renal failure symptoms in...

Subject

Metabolome

Gut flora

Microbiome

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