Digestive system is a potential route of COVID-19: an analysis of single-cell coexpression pattern of key proteins in viral entry process

Zhang, Hao; Kang, Zijian; Gong, Haiyi; Xu, Da; Wang, Jing; Li, Zhixiu; Li, Zifu; Cui, Xinggang; Xiao, Jianru; Zhan, Jian; Meng, Tong; Zhou, Wang; Liu, Jianmin; Xu, Huji

doi:10.1136/gutjnl-2020-320953

Public

Digestive system is a potential route of COVID-19: an analysis of single-cell coexpression pattern of key proteins in viral entry process

Published in Gut • Apr 2, 2020

Authors:

Hao Zhang

Zijian Kang

Haiyi Gong

Abstract

Objective Since December 2019, a newly identified coronavirus (severe acute respiratory syndrome coronavirus (SARS-CoV-2)) has caused outbreaks of pneumonia in Wuhan, China. SARS-CoV-2 enters host cells via cell receptor ACE II (ACE2) and the transmembrane serine protease 2 (TMPRSS2). In order to id...

Subject

TMPRSS2

Biology

Coronavirus

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