A review on the cleavage priming of the spike protein on coronavirus by angiotensin-converting enzyme-2 and furin

Hasan, Anwarul; Ahamad Paray, Bilal; Hussain, Arif; Ali Qadir, Fikry; Attar, Farnoosh; Mohammad Aziz, Falah; Sharifi, Majid; Derakhshankhah, Hossein; Rasti, Behnam; Mehrabi, Masoumeh; Shahpasand, Koorosh; Akbar Saboury, Ali; Falahati, Mojtaba

doi:10.1080/07391102.2020.1754293

Public

A review on the cleavage priming of the spike protein on coronavirus by angiotensin-converting enzyme-2 and furin

Published in Journal of Biomolecular Structure and Dynamics • Apr 10, 2020

Authors:

Anwarul Hasan

Bilal Ahamad Paray

Arif Hussain

Abstract

The widespread antigenic changes lead to the emergence of a new type of coronavirus (CoV) called as severe acute respiratory syndrome (SARS)-CoV-2 that is immunologically different from the previous circulating species. Angiotensin-converting enzyme-2 (ACE-2) is one of the most important receptors o...

Subject

Furin

Coronavirus

Cleavage (geology)

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