Structure of the RNA-dependent RNA polymerase from COVID-19 virus

Gao, Yan; Yan, Liming; Huang, Yucen; Liu, Fengjiang; Zhao, Yao; Cao, Lin; Wang, Tao; Sun, Qianqian; Ming, Zhenhua; Zhang, Lianqi; Ge, Ji; Zheng, Litao; Zhang, Ying; Wang, Haofeng; Zhu, Yan; Zhu, Chen; Hu, Tianyu; Hua, Tian; Zhang, Bing; Yang, Xiuna; Li, Jun; Yang, Haitao; Liu, Zhijie; Xu, Wenqing; W. Guddat, Luke; Wang, Quan; Lou, Zhiyong; Rao, Zihe

doi:10.1126/science.abb7498

Public

Structure of the RNA-dependent RNA polymerase from COVID-19 virus

Published in Science • Apr 10, 2020

Authors:

Yan Gao

Liming Yan

Yucen Huang

Abstract

A novel coronavirus [severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2)] outbreak has caused a global coronavirus disease 2019 (COVID-19) pandemic, resulting in tens of thousands of infections and thousands of deaths worldwide. The RNA-dependent RNA polymerase [(RdRp), also named nsp12] is...

Subject

Virology

RNA-dependent RNA polymerase

Polymerase

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