Spatial heterogeneity of oxygenation and haemodynamics in breast cancer resolved in vivo by conical multispectral optoacoustic mesoscopy

Li, Jiao; Chekkoury, Andrei; Prakash, Jaya; Glasl, Sarah; Vetschera, Paul; Koberstein‐Schwarz, Benno; Olefir, Ivan; Gujrati, Vipul; Omar, Murad; Ntziachristos, Vasilis

doi:10.1038/s41377-020-0295-y

Public

Spatial heterogeneity of oxygenation and haemodynamics in breast cancer resolved in vivo by conical multispectral optoacoustic mesoscopy

Published in Light Science & Applications • Apr 13, 2020

Authors:

Jiao Li

Andrei Chekkoury

Jaya Prakash

Abstract

The characteristics of tumour development and metastasis relate not only to genomic heterogeneity but also to spatial heterogeneity, associated with variations in the intratumoural arrangement of cell populations, vascular morphology and oxygen and nutrient supply. While optical (photonic) microscop...

Subject

In vivo

Biomedical engineering

Breast cancer

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