Ru( <scp>ii</scp> )-Naphthoquinone complexes with high selectivity for triple-negative breast cancer

M. Oliveira, Katia; J. Peterson, Erica; C. Carroccia, Murilo; R. Cominetti, Márcia; M. Deflon, Victor; P. Farrell, Nicholas; A. Batista, Alzir; S. Corrêa, Rodrigo

doi:10.1039/d0dt01091j

Public

Ru( ii )-Naphthoquinone complexes with high selectivity for triple-negative breast cancer

Published in Dalton Transactions • Jan 1, 2020

Authors:

Katia M. Oliveira

Erica J. Peterson

Murilo C. Carroccia

Abstract

Six new ruthenium(ii) complexes with lapachol (Lap) and lawsone (Law) with the general formula [Ru(L)(P-P)(bipy)]PF6, where L = Lap or Law, P-P = 1,2'-bis(diphenylphosphino)ethane (dppe), 1,4'-bis(diphenylphosphino)butane (dppb), 1,1'-bis(diphenylphosphino)ferrocene (dppf) and bipy = 2,2'-bipyridine...

Subject

Selectivity

Triple-negative breast cancer

Chemistry

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