Ten-Year Results of FAST: A Randomized Controlled Trial of 5-Fraction Whole-Breast Radiotherapy for Early Breast Cancer

Murray Brunt, Adrian; Haviland, Joanne; Sydenham, Mark; K. Agrawal, R.; Algurafi, Hafiz; Alhasso, Abdulla; Barrett‐Lee, Peter; Bliss, Peter; Bloomfield, David; Bowen, Joanna; M. Donovan, Ellen; Goodman, Andy; Harnett, Adrian; Hogg, Martin; Kumar, Sri; Passant, Helen; Quigley, Mary; Sherwin, Liz; L. Stewart, Alan; Syndikus, Isabel; Tremlett, Jean; Tsang, Y.; Venables, Karen; Wheatley, Duncan; M. Bliss, Judith; Yarnold, John

doi:10.1200/jco.19.02750

Public

Ten-Year Results of FAST: A Randomized Controlled Trial of 5-Fraction Whole-Breast Radiotherapy for Early Breast Cancer

Published in Journal of Clinical Oncology • Jul 14, 2020

Authors:

Adrian Murray Brunt

Joanne Haviland

Mark Sydenham

Abstract

PURPOSE Previous studies of hypofractionated adjuvant whole-breast radiotherapy for early breast cancer established a 15- or 16-fraction (fr) regimen as standard. The FAST Trial (CRUKE/04/015) evaluated normal tissue effects (NTE) and disease outcomes after 5-fr regimens. Ten-year results are presen...

Subject

Medicine

Breast cancer

Radiation therapy

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