Guidelines and definitions for research on epithelial–mesenchymal transition

Yang, Jing; B. Antin, Parker; Berx, Geert; Blanpain, Cédric; Brabletz, Thomas; Bronner‐Fraser, Marianne; Campbell, Kyra; Cano, Amparo; Casanova, Jordi; Christofori, Gerhard; Dedhar, Shoukat; Derynck, Rik; L. Ford, Heide; Fuxe, Jonas; García de Herreros, Antonio; J. Goodall, Gregory; Hadjantonakis, Anna‐Katerina; Yun‐Ju Huang, Ruby; Kalcheim, Chaya; Kalluri, Raghu; Kang, Yibin; Khew‐Goodall, Yeesim; Levine, Herbert; Liu, Jinsong; D. Longmore, Gregory; A. Mani, Sendurai; Massagué, Joan; Mayor, Roberto; R. McClay, David; E. Mostov, Keith; F. Newgreen, Donald; Ángela Nieto, M.; Puisieux, Alain; B. Runyan, Raymond; Savagner, Pierre; Z. Stanger, Ben; P. Stemmler, Marc; Takahashi, Yoshiko; Takeichi, Masatoshi; Théveneau, Eric; Paul Thiery, Jean; W. Thompson, Erik; A. Weinberg, Robert; D. Williams, Elizabeth; Xing, Jianhua; P. Zhou, Binhua; Sheng, Guojun

doi:10.1038/s41580-020-0237-9

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Guidelines and definitions for research on epithelial–mesenchymal transition

Published in Nature Reviews Molecular Cell Biology • Apr 16, 2020

Authors:

Jing Yang

Parker B. Antin

Geert Berx

Abstract

Epithelial-mesenchymal transition (EMT) encompasses dynamic changes in cellular organization from epithelial to mesenchymal phenotypes, which leads to functional changes in cell migration and invasion. EMT occurs in a diverse range of physiological and pathological conditions and is driven by a cons...

Subject

Terminology

Epithelial–mesenchymal transition

Conceptual framework

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