Human monoclonal antibodies block the binding of SARS-CoV-2 spike protein to angiotensin converting enzyme 2 receptor

Chen, Xiangyu; Ren, Li; Pan, Zhiwei; Qian, Chunfang; Yang, Yang; You, Renrong; Zhao, Jing; Liu, Pinghuang; Gao, Leiqiong; Li, Zhirong; Huang, Qizhao; Xu, Lifan; Tang, Jianfang; Qin, Tian; Yao, Wei; Li, Hu; Yan, Xiaofeng; Zhou, Xinyuan; Wu, Yuzhang; Deng, Kai; Zhang, Zheng; Qian, Zhaohui; Chen, Yaokai; Ye, Lilin

doi:10.1038/s41423-020-0426-7

Public

Human monoclonal antibodies block the binding of SARS-CoV-2 spike protein to angiotensin converting enzyme 2 receptor

Published in Cellular and Molecular Immunology • Apr 20, 2020

Authors:

Xiangyu Chen

Li Ren

Zhiwei Pan

Abstract

According to the World Health Organization (WHO) newly updated situation report on March 18th, 2020, the coronavirus disease 2019 (COVID-19) pandemic has confirmed 191,127 cases and claimed 7807 deaths worldwide. 1 6] Currently, there are no approved prophylactic vaccines or therapeutic drugs that a...

Subject

Monoclonal antibody

Spike Protein

Angiotensin-converting enzyme 2

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