Role of PI3K/AKT pathway in cancer: the framework of malignant behavior

Jiang, Ningni; Dai, Qijie; Su, Xiaorui; Fu, Jianjiang; Feng, Xuancheng; Peng, Juan

doi:10.1007/s11033-020-05435-1

Public

Role of PI3K/AKT pathway in cancer: the framework of malignant behavior

Published in Molecular Biology Reports • Apr 24, 2020

Authors:

Ningni Jiang

Qijie Dai

Xiaorui Su

Abstract

Given that the PI3K/AKT pathway has manifested its compelling influence on multiple cellular process, we further review the roles of hyperactivation of PI3K/AKT pathway in various human cancers. We state the abnormalities of PI3K/AKT pathway in different cancers, which are closely related with tumor...

Subject

PI3K/AKT/mTOR pathway

Protein kinase B

Cancer research

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