Dimethyl Sulfoxide: A Central Player Since the Dawn of Cryobiology, is Efficacy Balanced by Toxicity?

Awan, Maooz; Buriak, Iryna; A. Fleck, Roland; Fuller, Barry; Goltsev, Аnatoliy; Kerby, Julie; W. Lowdell, Mark; Měřička, Pavel; Petrenko, Oleksandr; Petrenko, Yuri; Rogulska, Olena; Stolzing, Alexandra; Stacey, Glyn

doi:10.2217/rme-2019-0145

Public

Dimethyl Sulfoxide: A Central Player Since the Dawn of Cryobiology, is Efficacy Balanced by Toxicity?

Published in Regenerative Medicine • Mar 1, 2020

Authors:

Maooz Awan

Iryna Buriak

Roland A. Fleck

Abstract

Dimethyl sulfoxide (DMSO) is the cryoprotectant of choice for most animal cell systems since the early history of cryopreservation. It has been used for decades in many thousands of cell transplants. These treatments would not have taken place without suitable sources of DMSO that enabled stable and...

Subject

Cryoprotectant

Dimethyl sulfoxide

Toxicity

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