Cytoskeletal-based mechanisms differently regulate &lt;i&gt;in vivo&lt;/i&gt; and &lt;i&gt;in vitro&lt;/i&gt; proplatelet formation

Bornert, Alicia; Boscher, Julie; Pertuy, Fabien; Eckly, Anita; Stegner, David; Strassel, Catherine; Gachet, Christian; Lanza, François; Léon, Catherine

doi:10.3324/haematol.2019.239111

Public

Cytoskeletal-based mechanisms differently regulate <i>in vivo</i> and <i>in vitro</i> proplatelet formation

Shared by NobleBlocks on Apr 23, 2020 • 12:00 AM UTC

Authors:

Alicia Bornert

Julie Boscher

Fabien Pertuy

Abstract

Platelets are produced by bone marrow megakaryocytes through cytoplasmic protrusions, named native proplatelets (nPPT), into blood vessels. Proplatelets also refer to protrusions observed in megakaryocyte culture (cPPT) that are morphologically different. Contrary to cPPT, the mechanisms of nPPT for...

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!