Interplay between Cellular Uptake, Intracellular Localization and the Cell Death Mechanism in Triphenylamine-Mediated Photoinduced Cell Death

Chennoufi, Rahima; N. Trinh, Duong; Simon, Françoise; Bordeau, Guillaume; Naud‐Martin, Delphine; Moussaron, Albert; Cinquin, Bertrand; Bougherara, Houcine; Rambaud, Béatrice; Tauc, Patrick; Frochot, Céline; Teulade‐Fichou, Marie‐Paule; Mahuteau‐Betzer, Florence; Deprez, Eric

doi:10.1038/s41598-020-63991-9

Public

Interplay between Cellular Uptake, Intracellular Localization and the Cell Death Mechanism in Triphenylamine-Mediated Photoinduced Cell Death

Published in Scientific Reports • Apr 23, 2020

Authors:

Rahima Chennoufi

Duong N. Trinh

Françoise Simon

Abstract

Triphenylamines (TPAs) were previously shown to trigger cell death under prolonged one- or two-photon illumination. Their initial subcellular localization, before prolonged illumination, is exclusively cytoplasmic and they translocate to the nucleus upon photoactivation. However, depending on their ...

Subject

Programmed cell death

Intracellular

Cell biology

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