SARS-CoV-2 productively infects human gut enterocytes

M. Lamers, Mart; Beumer, Joep; van der Vaart, Jelte; Knoops, Kèvin; Puschhof, Jens; I. Breugem, Tim; B. G. Ravelli, Raimond; Paul van Schayck, J.; Z. Mykytyn, Anna; Q. Duimel, Hans; van Donselaar, Elly; Riesebosch, Samra; J.H. Kuijpers, Helma; Schipper, Debby; J. van de Wetering, Willine; de Graaf, Miranda; Koopmans, Marion; Cuppen, Edwin; J. Peters, Peter; L. Haagmans, Bart; Clevers, Hans

doi:10.1126/science.abc1669

Public

SARS-CoV-2 productively infects human gut enterocytes

Published in Science • May 1, 2020

Authors:

Mart M. Lamers

Joep Beumer

Jelte van der Vaart

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can cause coronavirus disease 2019 (COVID-19), an influenza-like disease that is primarily thought to infect the lungs with transmission through the respiratory route. However, clinical evidence suggests that the intestine may present anot...

Subject

Enterocyte

Infectivity

Organoid

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